The Gunners currently sit top of their group with nine points after winning their opening three games in the competition.
Sporting are just three points behind and lost to Arsenal when the two sides met last month thanks to a goal from Danny Welbeck.
Unai Emerys side is currently on a 14-game unbeaten run that he will hope they can continue.
Alexandre Lacazette has been in good form (Photo by Sebastian Frej/MB Media/Getty Images)
When is Arsenal vs Sporting Lisbon?
The match is on Thursday 7 November with kick-off at 20.00 at the Emirates Stadium.
What TV channel is Arsenal vs Sporting Lisbon on?
BT Sport 2 will be showing the game live with coverage starting at 20.00.
Subscribers will also be able to stream the game by using the BT Sport app.
What are the odds? (Courtesy of William Hill)
Arsenal – 2/7
Draw – 9/2
Sporting Lisbon – 9/1
25 Oct 2018 – Europa League
Sporting Lisbon 0-1 Arsenal
26 Nov 1969 – Fairs Cup
Arsenal 3-0 Sporting Lisbon
29 Oct 1969 – Fairs Cup
Sporting Lisbon 0-0 Arsenal