The Curacao-born 18-year-old is considered, alongside Angel Gomes, to be Uniteds most exciting academy product and he impressed on the clubs tour to the United States last summer.
Chong scored twice in Uniteds 3-0 win against Sunderlands U23s on Friday and has been rewarded with a call-up to first team training.
The wingers promotion is likely down to the fact that Alexis Sanchez was absent from training.
The Chilean was a late substitute in Saturdays 2-2 draw with Chelsea on Saturday and was in line to start against the Old Lady at Old Trafford.
Marouane Fellaini, Jesse Lingard, Phil Jones and Scott McTominay were all absent.
More: Manchester United FC
Tuesdays game sees Cristiano Ronaldo return to Old Trafford for the second time since the 33-year-old completed a then-world record move to Real Madrid in 2009.
He returned four years later in 2013 and scored in a 2-1 win at the Theatre of Dreams with Jose Mourinhos Madrid side.